Botulinum toxin-type A: could it be an effective treatment option in intractable trigeminal neuralgia?

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Beneficial effects of botulinum toxin type A in trigeminal neuralgia.

Botulinum toxin has been thoroughly studied as a potential tool in the treatment of several pain syndromes. Therefore, we assessed the clinical effects of botulinum toxin type A injections in 12 patients with otherwise unresponsive idiopathic trigeminal neuralgia. Patients were infiltrated with 20-50 units of botulinum toxin in trigger zones. Those who presented with mandibular involvement were...

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Botulinum toxin in the treatment of trigeminal neuralgia

BACKGROUND Botulinum toxin type-A (BTX-A) has been successfully utilized to treat trigeminal neuralgia. In this study, through the use of a new technique, the efficacy of the injection of BTX-A to the maxillary and mandibular nerves was evaluated. METHODS A total of 27 patients were injected with 100 Units of BTX-A to the maxillary and mandibular nerves. Visual analogue scale score and pain f...

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A new treatment paradigm for trigeminal neuralgia using Botulinum toxin type A.

OBJECTIVES To review the current data for the use of Botulinum toxin type A (BoNT-A) in trigeminal neuralgia (TN) and to describe the preferred injection technique of BoNT-A in TN. To propose a new treatment paradigm for TN incorporating the use BoNT-A. DATA SOURCES MEDLINE and Google Scholar databases. REVIEW METHODS The current data on BoNT-A for TN were reviewed and analyzed for outcomes...

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Role of Botulinum Toxin Type-A (BTX-A) in the Management of Trigeminal Neuralgia

Trigeminal neuralgia (TN) is a clinical condition characterized by paroxysmal attacks of severe and electric shock-like pain along the distribution of one or more branches of the trigeminal nerve. Various medicinal or surgical modalities have been employed in the past with variable success. Newer methods were tried in search of permanent cure or long-lasting pain relief. The purpose of this pap...

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Epilepsy is an important disease that affects brain function, particularly in those under 3 years old. Uncontrolled seizures can affect cognitive function and quality of life. For these reasons, many trials have been conducted to investigate treatments for pediatric epilepsy. Currently, many antiepileptic drugs are available for the treatment of epilepsy, but cases of intractable epilepsy conti...

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ژورنال

عنوان ژورنال: The Journal of Headache and Pain

سال: 2013

ISSN: 1129-2369,1129-2377

DOI: 10.1186/1129-2377-14-92